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恶性黑色素瘤的肺门和纵隔淋巴结转移

Hilar and mediastinal lymph node metastases in malignant melanoma.

作者信息

Webb W R

出版信息

AJR Am J Roentgenol. 1979 Nov;133(5):805-10. doi: 10.2214/ajr.133.5.805.

DOI:10.2214/ajr.133.5.805
PMID:115264
Abstract

Of 65 patients with intrathoracic metastases from melanomon, 35 had metastasis to hilar or mediastinal nodes. In 28 of these 35, hilar and mediastinal lymph node enlargement was radiographically visible, hilar node enlargement was more commonly seen than mediastinal node enlargement. Pulmonary nodules were demonstrated radiographically in 25 of the 28 patients. Although lymph node enlargement was often asymmetric, symmetric hilar adenopathy mimicking sarcoidosis occurred in five of the 28 patients. Seven patients had unilateral involvement of lung and hilar and mediastinal nodes. In patients with melanoma, indirect metastatic spread via pulmonary nodules to hilar and mediastinal nodes may account for the frequent association of node metastases with lung nodules, the occurrence of intrathoracic adenopathy in the absence of extrathoracic node metastases, and the common finding of unilateral lung and nodal disease.

摘要

在65例黑色素瘤胸内转移患者中,35例有肺门或纵隔淋巴结转移。在这35例患者中,28例在影像学上可见肺门和纵隔淋巴结肿大,肺门淋巴结肿大比纵隔淋巴结肿大更常见。28例患者中有25例在影像学上显示有肺结节。虽然淋巴结肿大常不对称,但28例患者中有5例出现了类似结节病的对称性肺门淋巴结病。7例患者肺部、肺门和纵隔淋巴结单侧受累。在黑色素瘤患者中,通过肺结节间接转移至肺门和纵隔淋巴结可能是导致淋巴结转移与肺结节频繁相关、在无胸外淋巴结转移情况下出现胸内淋巴结病以及单侧肺和淋巴结疾病常见的原因。

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