McLoud T C, Kalisher L, Stark P, Greene R
AJR Am J Roentgenol. 1978 Sep;131(3):403-7. doi: 10.2214/ajr.131.3.403.
The clinical records of 1,071 cases of extrathoracic malignant neoplasms seen over a 2 year period sere reviewed: 163 had abnormal chest films, and 25 of these showed evidence of mediastinal and/or hilar lymph node metastases. The primary malignancies which metastasized to intrathoracic lymph nodes included eight tumors of the head and neck, 12 genitourinary malignancies, three carcinomas of the breast, and two malignant melanomas. The chest films were analyzed to determine the distribution of lymph node groups involved. Unilateral lymph node enlargement occurred in eight. The most frequently detected lymph node group was the right paratracheal chain (60%), while the subcarinal and posterior mediastinal groups were rarely affected. Of the 25 cases, 10 had radiographic evidence of hematogenous or lymphangitic metastases in addition in the lungs. Metastatic disease from extrathoracic neoplasms should always be considered in the differential diagnosis of hilar and mediastinal adenopathy.
回顾了两年内所见的1071例胸外恶性肿瘤的临床记录：163例胸片异常，其中25例显示有纵隔和/或肺门淋巴结转移的证据。转移至胸内淋巴结的原发性恶性肿瘤包括8例头颈部肿瘤、12例泌尿生殖系统恶性肿瘤、3例乳腺癌和2例恶性黑色素瘤。对胸片进行分析以确定受累淋巴结组的分布。8例出现单侧淋巴结肿大。最常检测到的淋巴结组是右气管旁链（60%），而隆突下和后纵隔组很少受累。在这25例中，10例除肺部外还有血行或淋巴管转移的影像学证据。在肺门和纵隔淋巴结肿大的鉴别诊断中，应始终考虑胸外肿瘤的转移疾病。
