[糖类抗原125在盆腔肿块中的作用。我们的经验]

[Role of Ca 125 in pelvic masses. Our experience].

作者信息

Rotondi M, Lauro C, Ammaturo F P, Guerriero V, Rasile M, Panariello S

机构信息

Instituto di Clinica Ostetrica e Ginecologica, Seconda Università degli Studi, Napoli.

出版信息

Minerva Ginecol. 2001 Feb;53(1 Suppl 1):51-4.

PMID:11526720

Abstract

BACKGROUND

The goal of our study is to plan a screening program for early detection of ovarian cancer through clinical examination, pelvic ultrasonography and serum Ca 125 dosage.

METHODS

Between January 1993 and June 1999, 436 patients have been submitted to ovarian cancer screening at the Obstetrics and Gynecology Institute of the Second University of Naples. All women were in postmenopausal period, older than 50 years and didn't show any gynecologic disease.

RESULTS

Clinical examination selected 41 patients (9.4%) with a pelvic mass; pelvic ultrasonography revealed ovarian or uterine mass (only subserous myoma) in 87 cases (19.9%). These patients were submitted to Ca 125 serum dosage; in three cases Ca 125 was higher than 65 U/ml and in 26 cases its value was between 35 and 65 U/ml. The remaining 58 patients showed Ca 125 values lower than 35 U/ml. Four patients with ovarian cancer have been detected with our screening program.

CONCLUSIONS

The authors conclude that pelvic ultrasonography and serum Ca 125 dosage are useful for the assessment of an early screening program of ovarian cancer.

摘要

背景

我们研究的目的是通过临床检查、盆腔超声检查和血清Ca 125检测来规划一项卵巢癌早期检测的筛查项目。

方法

1993年1月至1999年6月期间，436例患者在那不勒斯第二大学妇产科研究所接受了卵巢癌筛查。所有女性均处于绝经后，年龄超过50岁，且未表现出任何妇科疾病。

结果

临床检查发现41例（9.4%）有盆腔肿块；盆腔超声检查发现87例（19.9%）有卵巢或子宫肿块（仅浆膜下肌瘤）。这些患者接受了血清Ca 125检测；3例患者Ca 125高于65 U/ml，26例患者其值在35至65 U/ml之间。其余58例患者Ca 125值低于35 U/ml。通过我们的筛查项目检测出4例卵巢癌患者。