Iervolino P, Palmieri M, Rotondi M, D'Alessandro P, Iuliano R
Divisione di Ostetricia e Ginecologia, Ospedale S. Maria di Loreto Nuovo, Napoli.
Minerva Ginecol. 2001 Feb;53(1 Suppl 1):97-9.
To evaluate the clinical features, the surgical management and outcome of 20 patients with stage-I borderline ovarian tumors.
Twenty cases of FIGO stage-I ovarian tumors, aged from 31 to 58 years (mean 37 years) have been reviewed. All informations of clinical stage, surgical intervention and prognosis were achieved by reviewing hospital records. Minimal requirements for conservative management were adequate staging and complete information about the therapeutic options. Factors important in the choice of the treatment were, age, wish to preserve fertility, histologic type and grade, and the stage of the tumour.
Eleven of the 20 patients (55%) were at stage IA, 6 cases (30%) were at stage IB, 3 cases (15%) were at stage IC. Thirteen (65%) were with mucinous cystadenoma of borderline malignancy, 7 cases (35%) were of serous type. Thirteen patients underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH and BSO). Seven patients were treated with unilateral oophorectomy or unilateral salpingo-oophorectomy (USO). One patient underwent enucleation of ovarian tumor and biopsy of contralateral ovary. Any patient were treated with chemotherapy after operation. With a median follow up of two years, we observed no recurrence of carcinoma in women treated conservatively or in those treated more radically.
Conservative surgery remains a therapeutic option in selected patients with borderline ovarian tumors. Prolonged intensive follow-up is required for women treated conservatively for borderline malignant ovarian tumours.
评估20例Ⅰ期卵巢交界性肿瘤患者的临床特征、手术治疗及预后。
回顾了20例国际妇产科联盟（FIGO）Ⅰ期卵巢肿瘤患者，年龄31至58岁（平均37岁）。通过查阅医院记录获取临床分期、手术干预及预后的所有信息。保守治疗的最低要求是充分分期及有关治疗选择的完整信息。治疗选择中重要的因素包括年龄、保留生育功能的意愿、组织学类型和分级以及肿瘤分期。
20例患者中11例（55%）为ⅠA期，6例（30%）为ⅠB期，3例（15%）为ⅠC期。13例（65%）为交界性黏液性囊腺瘤，7例（35%）为浆液性类型。13例患者接受了全腹子宫切除术及双侧输卵管卵巢切除术（TAH和BSO）。7例患者接受了单侧卵巢切除术或单侧输卵管卵巢切除术（USO）。1例患者接受了卵巢肿瘤剥除术及对侧卵巢活检。术后无一例患者接受化疗。中位随访两年，我们观察到接受保守治疗或更激进治疗的女性均未出现癌症复发。
对于部分卵巢交界性肿瘤患者，保守手术仍是一种治疗选择。对于接受保守治疗的卵巢交界性恶性肿瘤女性，需要进行长期密切随访。
