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[氟中毒职业易感性的遗传标志物]

[Genetic markers of occupational susceptibility to fluorosis].

作者信息

Danilov I P, Protasov V V, Lotosh E A, Luzina F A

出版信息

Med Tr Prom Ekol. 2001(7):30-3.

Abstract

To determine markers showing propensity to occupational fluorosis, the authors studied prevalence of ABO, Rh, MN, ABH and Lewis phenotypes, systemic rhesus haplotypes in 229 workers engaged into aluminum production. Propensity to occupational fluorosis was marked by P (+), O (ABO) phenotypes. P (-) phenotype appeared to be a marker of resistance to fluorides exposure. The results obtained could be useful to forecast probability of fluorosis and to better this disease prevention.

摘要

为了确定显示职业性氟中毒倾向的标志物,作者研究了229名从事铝生产的工人的ABO、Rh、MN、ABH和Lewis血型表型以及系统性恒河猴单倍型。职业性氟中毒倾向以P(+)、O(ABO)血型表型为特征。P(-)血型表型似乎是对氟化物暴露有抗性的标志物。所获得的结果可能有助于预测氟中毒的可能性并改善这种疾病的预防。

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