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子宫颈上皮样平滑肌肉瘤

Epithelioid leiomyosarcoma of the uterine cervix.

作者信息

Gotoh T, Kikuchi Y, Takano M, Kita T, Ogata S, Aida S

机构信息

Department of Obstetrics and Gynecology, National Defense Medical College, Namiki 3-2, Tokorozawa, Saitama, 359-8513, Japan.

出版信息

Gynecol Oncol. 2001 Aug;82(2):400-5. doi: 10.1006/gyno.2001.6288.

DOI:10.1006/gyno.2001.6288
PMID:11531304
Abstract

BACKGROUND

Leiomyosarcomas with an epithelioid appearance arising in the uterine cervix are extremely rare neoplasms. We present a case of triple uterine cancer containing cervical epithelioid leiomyosarcoma.

CASE

A 72-year-old Japanese woman, gravida 1, para 1, 55 years in menopause, visited her local doctor due to atypical bleeding and the endometrial smear was suspect for malignancy. She was referred to our hospital. Endometrial curettage revealed endometrioid adenocarcinoma, G1, with a fragment of sarcomatous tumor. A total hysterectomy with bilateral salpingo-oophorectomy was performed. The histological findings revealed triple uterine cancer consisting of endometrial adenocarcinoma, cervical epithelioid leiomyosarcoma, and cervical squamous cell carcinoma.

CONCLUSION

This extremely rare case of triple uterine cancer containing cervical epithelioid leiomyosarcoma is the first report, to the best of our knowledge.

摘要

背景

子宫颈出现上皮样外观的平滑肌肉瘤是极其罕见的肿瘤。我们报告一例包含宫颈上皮样平滑肌肉瘤的三重子宫癌病例。

病例

一名72岁的日本女性,孕1产1,绝经55年,因非典型出血就诊于当地医生,子宫内膜涂片怀疑为恶性肿瘤。她被转诊至我院。子宫内膜刮除术显示为子宫内膜样腺癌,G1级,伴有肉瘤样肿瘤碎片。行全子宫切除术及双侧输卵管卵巢切除术。组织学检查结果显示为三重子宫癌,由子宫内膜腺癌、宫颈上皮样平滑肌肉瘤和宫颈鳞状细胞癌组成。

结论

据我们所知,这例包含宫颈上皮样平滑肌肉瘤的极其罕见的三重子宫癌病例为首例报道。

相似文献

1
Epithelioid leiomyosarcoma of the uterine cervix.子宫颈上皮样平滑肌肉瘤
Gynecol Oncol. 2001 Aug;82(2):400-5. doi: 10.1006/gyno.2001.6288.
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Epithelioid leiomyosarcoma of the uterine cervix: a case report and review of the literature.子宫颈上皮样平滑肌肉瘤:一例报告并文献复习
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An extremely rare case of adenoma malignum with large cystic tumor which resulted in urinary obstruction.一例极为罕见的恶性腺瘤合并巨大囊性肿瘤导致尿路梗阻的病例。
Gynecol Oncol. 2002 Feb;84(2):339-43. doi: 10.1006/gyno.2001.6530.
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Triple synchronous primary cervical, endometrial and ovarian cancer with four different histologic patterns.具有四种不同组织学模式的三重同步原发性宫颈癌、子宫内膜癌和卵巢癌。
Arch Gynecol Obstet. 2007 Dec;276(6):655-8. doi: 10.1007/s00404-007-0392-7. Epub 2007 May 31.
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Uterine cervical carcinosarcoma with heterologous mesenchymal component: a case report and review of the literature.具有异源间叶成分的子宫颈癌肉瘤:病例报告及文献复习。
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Verrucous carcinoma of the endometrium: case history, pathologic findings, brief review of literature and discussion.子宫内膜疣状癌:病例报告、病理结果、文献简要回顾及讨论
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引用本文的文献

1
Multimodality management of leiomyosarcoma of the cervix.子宫颈平滑肌肉瘤的多模态管理
Ecancermedicalscience. 2018 Apr 30;12:830. doi: 10.3332/ecancer.2018.830. eCollection 2018.
2
Leiomyosarcoma of cervix.宫颈平滑肌肉瘤
J Obstet Gynaecol India. 2013 Jun;63(3):211-2. doi: 10.1007/s13224-012-0191-3. Epub 2012 Oct 3.
3
Uncommon sarcomas of the uterine cervix: a review of selected entities.子宫颈罕见肉瘤:特定实体综述
Diagn Pathol. 2006 Sep 18;1:30. doi: 10.1186/1746-1596-1-30.