Gotoh T, Kikuchi Y, Takano M, Kita T, Ogata S, Aida S
Department of Obstetrics and Gynecology, National Defense Medical College, Namiki 3-2, Tokorozawa, Saitama, 359-8513, Japan.
Gynecol Oncol. 2001 Aug;82(2):400-5. doi: 10.1006/gyno.2001.6288.
Leiomyosarcomas with an epithelioid appearance arising in the uterine cervix are extremely rare neoplasms. We present a case of triple uterine cancer containing cervical epithelioid leiomyosarcoma.
A 72-year-old Japanese woman, gravida 1, para 1, 55 years in menopause, visited her local doctor due to atypical bleeding and the endometrial smear was suspect for malignancy. She was referred to our hospital. Endometrial curettage revealed endometrioid adenocarcinoma, G1, with a fragment of sarcomatous tumor. A total hysterectomy with bilateral salpingo-oophorectomy was performed. The histological findings revealed triple uterine cancer consisting of endometrial adenocarcinoma, cervical epithelioid leiomyosarcoma, and cervical squamous cell carcinoma.
This extremely rare case of triple uterine cancer containing cervical epithelioid leiomyosarcoma is the first report, to the best of our knowledge.
子宫颈出现上皮样外观的平滑肌肉瘤是极其罕见的肿瘤。我们报告一例包含宫颈上皮样平滑肌肉瘤的三重子宫癌病例。
一名72岁的日本女性,孕1产1,绝经55年,因非典型出血就诊于当地医生,子宫内膜涂片怀疑为恶性肿瘤。她被转诊至我院。子宫内膜刮除术显示为子宫内膜样腺癌,G1级,伴有肉瘤样肿瘤碎片。行全子宫切除术及双侧输卵管卵巢切除术。组织学检查结果显示为三重子宫癌,由子宫内膜腺癌、宫颈上皮样平滑肌肉瘤和宫颈鳞状细胞癌组成。
据我们所知,这例包含宫颈上皮样平滑肌肉瘤的极其罕见的三重子宫癌病例为首例报道。