Krupp P J, Lee F Y, Bohm J W, Batson H W, Diem J E, Lemire J E
Obstet Gynecol. 1975 Jul;46(1):84-8. doi: 10.1097/00006250-197507000-00016.
An evaluation and a critique of prognostic parameters and criteria involved in the classification and clinical staging of epidermoid carcinoma of the vulva are presented, comparing the FIGO system and a proposed more definitive system. Biostatistical as well as clinical evidence for an improved system is presented. The proposed system is based on statistically valid data, has good patient distribution, and an orderly progression for therapy and prognosis. In addition, it is well suited for computer programming and for the comparison of patients and therapy, as well as for delineating the natural history of vulvar cancer.
本文对外阴表皮样癌分类和临床分期中所涉及的预后参数及标准进行了评估与批判，比较了国际妇产科联盟（FIGO）系统和一个提议的更具确定性的系统。文中给出了支持改进系统的生物统计学及临床证据。提议的系统基于具有统计学效度的数据，患者分布良好，治疗与预后呈有序进展。此外，它非常适合计算机编程以及患者与治疗的比较，还适合描绘外阴癌的自然病程。
