外阴癌的预后因素。

Prognostic factors in carcinoma of the vulva.

作者信息

Boyce J, Fruchter R G, Kasambilides E, Nicastri A D, Sedlis A, Remy J C

出版信息

Gynecol Oncol. 1985 Mar;20(3):364-77. doi: 10.1016/0090-8258(85)90218-5.

Abstract

The clinical and pathologic characteristics of epidermoid carcinoma of the vulva in 84 women treated by vulvectomy were evaluated in relation to inguinal node status and survival. Tumor diameter, depth of invasion, clinical node status, vascular invasion, and pattern of invasion were all individually correlated with the pathologic status of the inguinal nodes. However, when evaluated in combination, only the clinical status of the inguinal nodes, the depth of invasion, and the pattern of invasion (in this order of significance) were predictive of pathologic inguinal node status. Tumor diameter, inguinal node status, depth of invasion, pattern of invasion, and vascular invasion were individually correlated with survival. When evaluated in combination, the clinical diameter of the lesion was the most important predictor of survival; depth of invasion and vascular invasion contributed additional information.

摘要

对84例行外阴切除术治疗的女性外阴表皮样癌的临床和病理特征进行评估，以了解其与腹股沟淋巴结状态及生存情况的关系。肿瘤直径、浸润深度、临床淋巴结状态、血管浸润及浸润方式均分别与腹股沟淋巴结的病理状态相关。然而，综合评估时，只有腹股沟淋巴结的临床状态、浸润深度及浸润方式（按此重要性顺序）能够预测腹股沟淋巴结的病理状态。肿瘤直径、腹股沟淋巴结状态、浸润深度、浸润方式及血管浸润均分别与生存情况相关。综合评估时，病变的临床直径是生存的最重要预测因素；浸润深度和血管浸润提供了额外信息。