Szafranowa H, Lastowska K, Skowroński J
Pol J Pharmacol Pharm. 1975 Apr-Jun;27(2):169-76.
Appropriate conditions for the indirect measurement of blood pressure in rat were determined. The value of 0.78 was found as a correlation factor between the direct and the indirect measurement methods. The direct and indirect methods were compared on hypertensive phenylephrine effects. Good dose-effect correlation of hydralazine by the indirect measurement was found. Our results indicate that the indirect measurement is suitable for the determination of hyper- and hypotensive drugs.
确定了大鼠间接测量血压的适宜条件。发现直接测量法与间接测量法之间的相关系数为0.78。比较了直接法和间接法对去氧肾上腺素高血压效应的影响。发现通过间接测量法,肼屈嗪有良好的剂量效应相关性。我们的结果表明,间接测量法适用于测定降压药和升压药。