Sherstnev V V, Gruden' M A, Storozheva Z I, Proshin A T
P. K. Anokhin Research Institute of Normal Physiology, Russian Acad. Med. Sci., 103009, Moscow, B. Nikitskaya, 6, Russia.
Ross Fiziol Zh Im I M Sechenova. 2001 Jun;87(6):752-61.
Following elaboration of long-term habituation to a startle-response, antibodies to neurotrophic factor protein S100b exerted selective and dose-dependent influence on different learning processes and memory of learned behavioural patterns in adult rats. S100b increased at all stages of behavioural skill development in hippocampus, hypothalamus, frontal cortex, cerebellar hemispheres and vermis, basal ganglia.
在对惊跳反应形成长期习惯化后，针对神经营养因子蛋白S100b的抗体对成年大鼠不同的学习过程以及习得行为模式的记忆产生了选择性和剂量依赖性影响。在海马体、下丘脑、额叶皮质、小脑半球和蚓部、基底神经节等行为技能发展的各个阶段，S100b均有所增加。
