Fedorova V A, Sameliia Zh G, Devdariani Z L, Shvedun G P
Mikrob Plague Control Institute, Saratov.
Mol Gen Mikrobiol Virusol. 2001(3):28-35.
Hybridomas producing monoclonal antibodies (MAb) to Yersinia pseudotuberculosis, serovars I-IV, responsible for serovar appurtenance, were obtained. Virtually all MAbs reacted with protein antigens in immunoblotting. The only exclusion was MAb 3A2 presumably reacting with a glycoprotein epitope of complex structure. Variability of Y. pseudotuberculosis antigenic structure, depending on culturing temperature, was confirmed. Polypeptides with mono- or polydetermined antigenic specificity were determined using MAbs.
