Gandhi N S, Jizhang C, Khoshnood K, Fuying X, Shanwen L, Yaoruo L, Bin Z, Haechou X, Chongjin T, Yan W, Wensen W, Dungxing H, Chong C, Shuhua X, Hawdon J M, Hotez P J
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
J Parasitol. 2001 Aug;87(4):739-43. doi: 10.1645/0022-3395(2001)087[0739:EONAHI]2.0.CO;2.
Hookworm is highly endemic to Hainan Province, an island located in the South China Sea. To investigate the prevalence and intensity of infection in the area, the village of Xiulongkan was surveyed between April and July 1998. A cross-sectional study was conducted in which fecal samples of 80% of the village residents (631 individuals) were tested for the presence of helminth eggs. Hookworm was the predominant intestinal helminth in Xiulongkan, where it was determined that 60% of those tested were infected. Necator americanus was the predominant species of hookworm in this population. The prevalence of hookworm increased with age, and then leveled to a plateau for ages 41 yr and up. This observation was in contrast to infections with Ascaris lumbricoides, where the highest prevalences occurred among school-aged children. Women had a significantly higher prevalence of hookworm than men and this difference emerged in early adulthood. The intensity of hookworm infection also significantly increased with age, with the highest intensity infections occurring among middle-aged and elderly residents. Females were more likely to have moderate or heavy infections, whereas males were more likely to have light infections. The rates of hookworm transmission are particularly high among the middle-aged and elderly residents of Xiulongkan.
钩虫在位于中国南海的岛屿——海南省高度流行。为调查该地区的感染率和感染强度，于1998年4月至7月对修龙坎村进行了调查。开展了一项横断面研究，检测了该村80%居民（631人）粪便样本中的蠕虫卵。钩虫是修龙坎村主要的肠道蠕虫，检测发现60%的受检者受到感染。美洲板口线虫是该人群中钩虫的主要种类。钩虫感染率随年龄增长而上升，41岁及以上人群感染率趋于平稳。这一观察结果与蛔虫感染情况相反，蛔虫感染率在学龄儿童中最高。女性钩虫感染率显著高于男性，这种差异在成年早期就已出现。钩虫感染强度也随年龄显著增加，中年及老年居民感染强度最高。女性更易出现中度或重度感染，而男性更易出现轻度感染。修龙坎村中年及老年居民的钩虫传播率尤其高。
