Yong W, Guangjin S, Weitu W, Shuhua X, Hotez P J, Qiyang L, Haichou X, Xiaomei Y, Xiaoming L, Bin Z, Hawdon J M, Li C, Hong J, Chunmei H, Zheng F
Anhui Institute of Parasitic Diseases, Wuhu, China.
Southeast Asian J Trop Med Public Health. 1999 Dec;30(4):692-7.
Hookworm infection has traditionally been highly endemic to Anhui Province, China. Zhongzhou village in southwestern Anhui was identified as an endemic focus of infection caused by the hookworm Ancylostoma duodenale. This species was found to predominate over Necator americanus in ratios ranging from 35:1 based on the recovery of third-stage infective larvae (L,) to 21:1 based on the recovery of adult hookworms after anthelmintic chemotherapy. The overall prevalence of Ancylostoma infection in Zhongzhou was 33.2% with a greater prevalence among males. Unlike the age-associated prevalence patterns for N. americanus in Hainan and other southern Chinese provinces that show increasing prevalence with age and the highest prevalence among the elderly, the age-associated prevalence for A. duodenale in Zhongzhou exhibited a peak in middle-aged adults with subsequent decline. The age-associated intensity pattern exhibited a similar trend although the most of the hookworm infections were light or moderate infections as defined by quantitative egg counts.
钩虫感染在中国安徽省一直是高度地方性流行疾病。皖南西南部的中洲村被确定为由十二指肠钩口线虫引起的感染地方性疫源地。发现该物种在感染率上占优势，超过美洲板口线虫，基于三期感染性幼虫（L3）的回收率，比例从35:1到驱虫化疗后成虫钩虫的回收率为21:1。中洲十二指肠钩口线虫感染的总体患病率为33.2%，男性患病率更高。与中国海南和其他南方省份美洲板口线虫的年龄相关患病率模式不同，后者显示患病率随年龄增长而增加，老年人中患病率最高，而中洲十二指肠钩口线虫的年龄相关患病率在中年成年人中达到峰值，随后下降。年龄相关的感染强度模式呈现出类似趋势，尽管根据定量虫卵计数，大多数钩虫感染为轻度或中度感染。
