Osawa M, Hongo K, Tanaka Y, Nakamura Y, Kitazawa K, Kobayashi S
Division of Neurosurgery, National Nagano Hospital, Ueda, Japan.
Acta Neurochir (Wien). 2001;143(7):655-63; discussion 663-4. doi: 10.1007/s007010170043.
The purpose of this study is to evaluate the therapeutic value of our surgical treatment of subarachnoid haemorrhage in a large series with standardized surgical principles.
Results of 2055 direct operations on ruptured intracranial aneurysms, treated in our institutions, where surgical indications, instruments and techniques were standardized, between 1988 and 1998, were retrospectively evaluated and outcome of the patients was discussed; cases treated by intravascular procedures were excluded.
According to the evaluation at discharge, 1083 (52.7%) patients were excellent, 324 (15.8%) good and 223 (10.9%) fair. There were 160 (7.8%) patients of poor outcome and the remaining 265 (12.9%) died. There were no differences in the outcome between pre-operative Hunt & Kosnik grade I and II, Fisher Scale 1 and 2, anterior circulation aneurysms and posterior circulation aneurysms except those at and around the basilar bifurcation, men and women, and those clipped and not clipped.
The factors related to poor outcomes were, age of 60 years or over, pre-operative Hunt & Kosnik grade II or more, Fisher Scale 3 or more, aneurysm size over 15 mm in diameter, and location at and around the basilar artery bifurcation. The results presented in this study show the status of our direct surgical management of subarachnoid haemorrhage in a large series with standardized surgical principles and procedures.
本研究旨在通过一系列遵循标准化手术原则的手术,评估我们对蛛网膜下腔出血的治疗价值。
回顾性评估1988年至1998年间在我们机构接受治疗的2055例破裂颅内动脉瘤直接手术的结果,这些手术的手术指征、器械和技术均已标准化,并讨论患者的预后;排除血管内治疗的病例。
根据出院时的评估,1083例(52.7%)患者预后极佳,324例(15.8%)良好,223例(10.9%)尚可。160例(7.8%)患者预后较差,其余265例(12.9%)死亡。术前Hunt & Kosnik分级为I级和II级、Fisher分级为1级和2级、前循环动脉瘤和后循环动脉瘤(除基底动脉分叉处及其周围)、男性和女性、夹闭和未夹闭的患者之间,预后无差异。
与预后不良相关的因素包括:60岁及以上、术前Hunt & Kosnik分级为II级或更高、Fisher分级为3级或更高、动脉瘤直径超过15 mm以及位于基底动脉分叉处及其周围。本研究结果显示了我们在遵循标准化手术原则和程序的情况下,对大量蛛网膜下腔出血患者进行直接手术治疗的现状。