片剂生产中作为直接压片干黏合剂的某些材料的研究。第1部分：流动性质和吸水性。
Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 1: flow properties and water sorption.
作者信息
Asker A F, Saied K M, Abdel-Khalek M M
出版信息
Pharmazie. 1975 Mar;30(3):181-5.
PMID:1153475
Abstract
Four substances were evaluated for their potential usefulness as dry binders for direct compression techniques in tablet making. The flow properties of these substances including angle of repose, timed delivery through an orifice and compressibility were determined. The effect of particle size of the binder on its flow properties was investigated. Comparative rates of water sorption demonstrated by the various substances evaluated as dry binders were also determined.
摘要
对四种物质作为片剂直接压片技术的干黏合剂的潜在用途进行了评估。测定了这些物质的流动性质，包括休止角、通过孔口的定时输送和可压缩性。研究了黏合剂粒径对其流动性质的影响。还测定了作为干黏合剂评估的各种物质的比较吸湿率。
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