Asker A F, Saied K M, Abdel-Khalek M M
Pharmazie. 1975 Jul;30(7):463-5.
The effect of addition of ascorbic acid, which is a drug known to be difficult to compress directly, on the self-binding efficiency of tragacanth, Carbowax 4000, Plasdone, and mannitol were investigated. The flow properties of ascorbic acid of different particle sizes were determined since they would affect the flowability of the binders investigated and would help to determine the optimum particle size of the drug required for maximum binding efficiency.
研究了添加抗坏血酸（一种已知难以直接压片的药物）对黄芪胶、聚乙二醇4000、聚维酮和甘露醇自结合效率的影响。测定了不同粒径抗坏血酸的流动性，因为它们会影响所研究粘合剂的流动性，并有助于确定实现最大结合效率所需药物的最佳粒径。
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