Berghot M A
Department of Chemistry, Faculty of Science, Mansoura University, Egypt.
Arch Pharm Res. 2001 Aug;24(4):263-9. doi: 10.1007/BF02975089.
Diazepamoxadiazoles 4, 5, 6, 12, 14 and 22 were prepared with the binary form system. Diazepamthiadiazoles 15, 20 and Diazepamtriazoles 7, 8, 9, 17, 18, 19 and 21 were also shapely synthesized. Some of these compounds were screened to test their antibacterial activity against E. coli and B. subtilis compounds 15 and 20 show potent activity against these bacteria.
地西泮恶二唑4、5、6、12、14和22是用二元体系制备的。地西泮噻二唑15、20以及地西泮三唑7、8、9、17、18、19和21也被成功合成。对其中一些化合物进行了筛选，以测试它们对大肠杆菌和枯草芽孢杆菌的抗菌活性，化合物15和20对这些细菌显示出强效活性。
