从人参中分离出的人参三醇的体外抗幽门螺杆菌活性。
In vitro anti-Helicobacter pylori activity of panaxytriol isolated from ginseng.
作者信息
Bae E A, Han M J, Baek N I, Kim D H
机构信息
Department of Food and Nutrition, Kyung Hee University, Seoul, Korea.
出版信息
Arch Pharm Res. 2001 Aug;24(4):297-9. doi: 10.1007/BF02975095.
PMID:11534760
Abstract
This study investigated the effect that some polyacetylenes and protopanaxatriol, which were isolated from heated ginseng (family Araliaceae), have on inhibiting Helicobacter pylori (HP) growth. Among the compounds tested, panaxytriol was quite effective in inhibiting HP growth with an MIC of 50 microg/ml. Ginsenoside Rh1 and protopanaxatriol weakly inhibited H+/K+-ATPase from a rat stomach.
摘要
本研究调查了从加热人参（五加科）中分离出的一些聚乙炔和原人参三醇对抑制幽门螺杆菌（HP）生长的作用。在所测试的化合物中，人参三醇对抑制HP生长相当有效，其最低抑菌浓度（MIC）为50微克/毫升。人参皂苷Rh1和原人参三醇对大鼠胃中的H+/K+-ATP酶有微弱抑制作用。
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