Harbord M
Department of Paediatrics and Child Health, Flinders Medical Centre, Bedford Park, SA, Australia.
J Clin Neurosci. 2001 Sep;8(5):421-2. doi: 10.1054/jocn.2000.0753.
Two intellectually disabled adults with Angelman Syndrome are reported who developed intermittent episodes of a severe resting tremor, cogwheel rigidity and bradykinesia in their late teens. The Parkinsonism was not due to medications and there was a dramatic improvement with levodopa therapy. The association between Angelman Syndrome and Parkinsonism has not previously been described.
据报道，两名患有天使综合征的成年智障患者在十几岁后期出现了严重静止性震颤、齿轮样强直和运动迟缓的间歇性发作。帕金森症并非由药物引起，左旋多巴治疗后有显著改善。此前尚未描述过天使综合征与帕金森症之间的关联。
