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一例因脑室内神经囊尾蚴病继发梗阻性脑积水而行脑室腹腔分流术后出现可逆性帕金森综合征的患者

Reversible parkinsonism following ventriculoperitoneal shunt in a patient with obstructive hydrocephalus secondary to intraventricular neurocysticercosis.

作者信息

Prashantha D K, Netravathi M, Ravishankar S, Panda Samhita, Pal Pramod Kumar

机构信息

Department of Neurology, National Institute of Mental Health & Neurosciences, Bangalore, India.

出版信息

Clin Neurol Neurosurg. 2008 Jul;110(7):718-21. doi: 10.1016/j.clineuro.2008.03.008. Epub 2008 Apr 25.

DOI:10.1016/j.clineuro.2008.03.008
PMID:18440127
Abstract

Parkinsonism with evidence of midbrain dysfunction has been reported in a few patients with aqueductal stenosis after placement of ventriculoperitoneal (VP) shunt. The response to levodopa is variable. We report a patient with neurocysticercosis of the fourth ventricle who developed transient parkinsonism without evidence of midbrain dysfunction after placement of a VP shunt. The frequency of tremor was 5-5.5 Hz. Though the response to levodopa was initially slow, later it was significant, and after 3 months he was asymptomatic without levodopa. The exact pathophysiology of parkinsonism in our patient remained obscure.

摘要

在少数患有导水管狭窄的患者中,在进行脑室腹腔(VP)分流术后出现了伴有中脑功能障碍证据的帕金森综合征。对左旋多巴的反应各不相同。我们报告了一名患有第四脑室神经囊尾蚴病的患者,在进行VP分流术后出现了短暂性帕金森综合征,但没有中脑功能障碍的证据。震颤频率为5 - 5.5赫兹。虽然最初对左旋多巴的反应较慢,但后来效果显著,3个月后未服用左旋多巴时他已无症状。我们患者帕金森综合征的确切病理生理学仍不清楚。

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