Cabradilla C D, Toliver A P
Physiol Chem Phys. 1975;7(2):153-65.
The nature of the nascent DNA-membrane complexes isolated from synchronized HeLa cells was examined. It was found that membrane-associated DNA is not the result of repair replication. A study of the stability of the complexes to various degradative agents and enzymes suggest that the DNA is associated with a structure which is composed of a lipoprotein. An examination of the physical structure of this DNA indicates that it might be a "nicked" duplex with a base content similar to that of the bulk DNA.
对从同步化的HeLa细胞中分离出的新生DNA-膜复合物的性质进行了研究。发现与膜相关的DNA并非修复复制的结果。对复合物对各种降解剂和酶的稳定性研究表明，DNA与一种由脂蛋白组成的结构相关联。对这种DNA物理结构的检查表明，它可能是一种“带切口”的双链体，其碱基含量与大部分DNA相似。
