器官特异性自身免疫性疾病：耐受性刺激的缺乏。 - Suppr

Organ-specific autoimmune disease: a deficiency of tolerogenic stimulation.

作者信息

Lesage S, Goodnow C C

机构信息

Australian Cancer Research Foundation Genetics Lab, Medical Genome Centre, John Curtin School of Medical Research, Canberra, ACT 2601, Australia.

出版信息

J Exp Med. 2001 Sep 3;194(5):F31-6. doi: 10.1084/jem.194.5.f31.

DOI:10.1084/jem.194.5.f31

PMID:11535640

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2195936/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9847/2195936/6cfce8060871/JEM011158.f1.jpg

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Organ-specific autoimmune disease: a deficiency of tolerogenic stimulation.器官特异性自身免疫性疾病：耐受性刺激的缺乏。

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Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice.B7-2缺陷型非肥胖糖尿病（NOD）小鼠自发性自身免疫性周围神经病的发生

J Exp Med. 2001 Sep 3;194(5):677-84. doi: 10.1084/jem.194.5.677.

Pathways for self-tolerance and the treatment of autoimmune diseases.

Lancet. 2001 Jun 30;357(9274):2115-21. doi: 10.1016/s0140-6736(00)05185-0.

Role of genetic factors in organ-specific autoimmune diseases induced by manipulating the thymus or T cells, and not self-antigens.遗传因素在通过操纵胸腺或T细胞而非自身抗原诱导的器官特异性自身免疫性疾病中的作用。

Rev Immunogenet. 2000;2(1):147-53.

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide.由激动剂自身肽诱导的CD4+CD25+调节性T细胞的胸腺选择。

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Organ-specific autoimmune disease: a deficiency of tolerogenic stimulation.

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