Debnam J W, Staple T W
Radiology. 1975 Sep;116(3):607-9. doi: 10.1148/116.3.607.
Trephine bone biopsies were performed in 67 patients. Routine radiography, laminagraphy, and radioisotopic techniques were employed to determine areas of involvement and exact sites for biopsy. Sites were selected on the basis of accessibility, possible complications, and chances of recovering diagnostic material. The biopsy material was informative in 81% of patients. One controllable hemorrhage, one temporary sinus tract, a small pneumothorax requiring no therapy, and two benign vasovagal responses were the only complications. Widespread malignant disease and osteomyelitis, particularly disk-space infection, are the most suitable lesions for trephine biopsy.
对67例患者进行了环钻骨活检。采用常规放射照相、体层摄影和放射性同位素技术来确定受累区域及活检的确切部位。根据可达性、可能的并发症以及获取诊断材料的机会来选择活检部位。81%的患者活检材料具有诊断价值。仅出现1例可控性出血、1个临时窦道、1例无需治疗的小气胸和2例良性血管迷走反应等并发症。广泛的恶性疾病和骨髓炎，尤其是椎间盘间隙感染，是最适合进行环钻活检的病变。
