Klein J S, Salomon G, Stewart E A
Department of Radiology, St Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
Radiology. 1996 Mar;198(3):715-20. doi: 10.1148/radiology.198.3.8628859.
To determine the utility of coaxial transthoracic needle biopsy (TNB) with use of a 20-gauge automated cutting biopsy needle in the diagnosis of thoracic lesions.
A retrospective review was performed in 122 patients. Computed tomography was used to guide coaxial TNB, which was performed with aspirating (n = 87) and automated cutting (n = 99) needles. The sensitivities for malignant and benign lesions were determined, with a comparison of the relative yields from the two techniques.
The overall diagnostic yield for coaxial TNB was 88%. For malignancy the sensitivity was 95%, whereas a specific benign diagnosis was obtained in 91%. Although no difference was found for fine-needle aspiration versus core biopsy of malignant lesions (92% vs 86%), a statistically significant difference was found for benign lesions (44% vs 100%, P<.05). Pneumothorax occurred in 54%.
Coaxial TNB performed with an automated cutting needle helps provide a diagnosis in the majority of patients with focal chest disease and is particularly useful in the diagnosis of benign lesions.
确定使用20号自动切割活检针进行同轴经胸针吸活检（TNB）在胸部病变诊断中的效用。
对122例患者进行回顾性研究。采用计算机断层扫描引导同轴TNB，使用抽吸针（n = 87）和自动切割针（n = 99）进行操作。确定恶性和良性病变的敏感性，并比较两种技术的相对取材成功率。
同轴TNB的总体诊断成功率为88%。对于恶性病变，敏感性为95%，而良性病变的特异性诊断率为91%。虽然恶性病变的细针抽吸与粗针活检之间未发现差异（92%对86%），但良性病变存在统计学显著差异（44%对100%，P<0.05）。气胸发生率为54%。
使用自动切割针进行同轴TNB有助于为大多数局灶性胸部疾病患者提供诊断，尤其在良性病变的诊断中有用。
