Malacinski G M, Neff A W
Department of Biology, Indiana University, Bloomington 47405, USA.
Adv Space Res. 1984;4(12):315-23. doi: 10.1016/0273-1177(84)90576-3.
The development of animal systems is described in terms of a series of overlapping phases: pattern specification; differentiation; growth; and aging. The extent to which altered (micro) gravity (g) affects those phases is briefly reviewed for several animal systems. As a model, amphibian egg/early embryo is described. Recent data derived from clinostat protocols indicates that microgravity simulation alters early pattern specification (dorsal/ventral polarity) but does not adversely influence subsequent morphogenesis. Possible explanations for the absence of catastrophic microgravity effects on amphibian embryogenesis are discussed.
模式规范、分化、生长和衰老。本文简要回顾了重力改变（微重力）对几种动物系统中这些阶段的影响程度。以两栖类卵/早期胚胎作为模型进行了描述。来自回转器实验方案的最新数据表明，微重力模拟改变了早期模式规范（背/腹极性），但对随后的形态发生没有不利影响。文中还讨论了两栖类胚胎发育未出现灾难性微重力效应的可能原因。
