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镍和铬对大鼠针对T-1噬菌体免疫的抗体反应的抑制作用。

Inhibitory effect of nickel and chromium upon antibody response of rats to immunization with T-1 phage.

作者信息

Figoni R A, Treagan L

出版信息

Res Commun Chem Pathol Pharmacol. 1975 Jun;11(2):335-8.

PMID:1153878
Abstract

Nickel and chromium significantly depressed the circulating antibody response of rats immunized with a viral antigen (T-1 phage). Consistent suppression of antibody was observed in all metal-treated animals; the greatest decrease in antibody titers was noted in animals receiving metals two weeks prior to the initial antigen dose.

摘要

镍和铬显著抑制了用病毒抗原（T-1噬菌体）免疫的大鼠的循环抗体反应。在所有接受金属处理的动物中均观察到抗体的持续抑制；在初次给予抗原剂量前两周接受金属处理的动物中，抗体滴度下降最为明显。

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