Diedrich A, Drescher J, Nalishitij V, Spatenko J A, Rome J L, Grüber W
RWTH Aachen, Working Group for Non-Invasive Diagnostics, Germany.
J Gravit Physiol. 1995;2(1):P13-4.
The cardiovascular function in space seems to be normal. However, abnormalities of cardiovascular responses have been found during lower body negative pressure suction in space. The etiology of the cardiovascular deconditioning in space is still unknown. A previous study showed, that short periods of head down tilt (HDT-6 degrees) induce changes in the spectral pattern of heart rate variabilty (HRV) and an increase in the sympathethic activation caused by orthostatic stress. The aim of this study was to test following hypotheses: 1. The dynamic of heart rate variability is different in the head down tilt and supine positions. 2. The application of lower body negative pressure (LBNP) during head down tilt induces similar heart rate variability patterns like the standing position. 3. After short term head down tilt the cardiovascular response to lower body negative pressure stressor is altered.
太空环境中的心血管功能似乎正常。然而,在太空进行下体负压吸引时,已发现心血管反应存在异常。太空心血管功能失调的病因仍不明。先前的一项研究表明,短时间头低位倾斜(HDT - 6度)会引起心率变异性(HRV)频谱模式的变化,以及由直立位应激导致的交感神经激活增加。本研究的目的是检验以下假设:1. 头低位倾斜和仰卧位时心率变异性的动态变化不同。2. 头低位倾斜期间施加下体负压(LBNP)会诱发与站立位类似的心率变异性模式。3. 短期头低位倾斜后,对下体负压应激源的心血管反应会发生改变。