Pace N, Rahlmann D F, Smith A H
Environmental Physiology Laboratory, University of California, Berkeley 94720, USA.
Physiologist. 1984;27(6 Suppl):S71-2.
The size of individual skeletal muscles in mammals is well known to change with the degree of mechanical loading imposed on the muscle. Less clear has been the effect of changes in loading of the whole organism on size of the total skeletal musculature. Pitts and coworkers have provided valuable insights by dissection and weighing of the skeletal musculature of animals subjected to various chronic centrifugation, exercise and dietary regimens, and their recent findings are reported at this meeting. However, questions remain. Independently, our laboratory several years ago embarked on a systematic definition of body composition and energy metabolism changes as a function of sex and age in 5 species of small laboratory mammals, the mouse, hamster, rat, guinea pig and rabbit. Six animals of each sex were examined in 8 age cohorts ranging from 1 to 24 months for each of the 5 species.
哺乳动物个体骨骼肌的大小会随着施加在肌肉上的机械负荷程度而变化，这是众所周知的。而整个生物体负荷变化对总骨骼肌系统大小的影响则不太清楚。皮茨及其同事通过解剖和称量接受各种慢性离心、运动和饮食方案的动物的骨骼肌系统，提供了有价值的见解，他们的最新研究结果在本次会议上进行了报告。然而，问题仍然存在。几年前，我们实验室独立开展了一项系统研究，确定了5种小型实验哺乳动物（小鼠、仓鼠、大鼠、豚鼠和兔子）的身体成分和能量代谢变化与性别和年龄的关系。对这5个物种中的每一个物种，在1至24个月的8个年龄组中，对每种性别的6只动物进行了检查。
