Jelenko C
South Med J. 1975 Jul;68(7):887-92.
Following significant burn injury, severe translocations occur in the distribution of water and solute. These result in major deficits in functional extracellular fluid and circulating water volume which may result in shock. The weight of evidence suggests that resuscitational regimens must contain large quantities of water which should be at least isotonic with respect at sodium; and some evidence suggests that current resuscitational regimens may not provide sufficient potassium to maintain the normal relationship between intracellular and extracellular solute and to prevent sodium sequestration. It is clear, however, that most of the currently used resuscitational "formulas" are effective in restoring and maintaining water balance, renal function, cardiac output, and in preventing or correcting shock.
严重烧伤后，水和溶质分布会发生严重的移位。这会导致功能性细胞外液和循环血容量大幅减少，进而可能引发休克。大量证据表明，复苏方案必须包含大量水分，且这些水分相对于钠应至少为等渗；还有一些证据表明，目前的复苏方案可能无法提供足够的钾来维持细胞内和细胞外溶质的正常关系并防止钠潴留。然而，很明显，目前大多数使用的复苏“公式”在恢复和维持水平衡、肾功能、心输出量以及预防或纠正休克方面都是有效的。
