Rauws A G
Toxicology. 1975 May;4(2):195-202. doi: 10.1016/0300-483x(75)90098-0.
Using data obtained from pharmacokinetic experiments with bromide, illustrations are given of the application of pharmacokinetics to toxicological studies. Analog computers may be helpful, though not indispensable. The significance of ancillary pharmacokinetic investigations in the evaluation of toxicity studies is discussed.
利用从溴化物药代动力学实验中获得的数据,举例说明了药代动力学在毒理学研究中的应用。模拟计算机可能会有帮助,尽管并非必不可少。讨论了辅助药代动力学研究在毒性研究评估中的意义。