Rauws A G
Food Chem Toxicol. 1983 Aug;21(4):379-82. doi: 10.1016/0278-6915(83)90091-1.
The recent role of bromide as a residue in food and water necessitated its toxicological investigation. Although much was known already about the absorption, distribution and elimination of bromide, more data were required, especially for the rat. The pharmacokinetics in the rat were therefore investigated, with emphasis on cumulation and on the role of chloride in bromide elimination. This review recapitulates old and recent findings on the fate of bromide.
近期食品和水中溴化物作为残留物的情况使得有必要对其进行毒理学研究。尽管人们已经对溴化物的吸收、分布和排泄有了很多了解,但仍需要更多数据,尤其是关于大鼠的数据。因此,对大鼠的药代动力学进行了研究,重点是累积情况以及氯在溴化物排泄中的作用。本综述概括了关于溴化物去向的新旧研究结果。