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三种正畸粘合剂氟释放与吸收情况的体外研究

An ex vivo investigation into the fluoride release and absorption profiles of three orthodontic adhesives.

作者信息

Coonar A K, Jones S P, Pearson G J

机构信息

Department of Orthodontics, Eastman Dental Institute for Oral Health Care Sciences, University College London, UK.

出版信息

Eur J Orthod. 2001 Aug;23(4):417-24. doi: 10.1093/ejo/23.4.417.

Abstract

Prevention of peri-bracket decalcification is essentially mediated by effective oral hygiene, which is patient dependent. The potential to compensate for poor oral hygiene may be through the release of free fluoride ions from direct bonding agents. It is well established that glass ionomer cements (GICs) release free fluoride ions which may be replenished by exposure to fluoride containing solutions. The aim of this ex vivo study was to compare the fluoride release and absorption profiles of a recently developed low fusion, monophase GIC, Limerick glass, with two materials in common clinical use, namely, Fuji-Ortho L.C. and Concise. Ten test specimens of each material were fabricated and stored in deionized water at 37 degrees C. The concentration of fluoride release was measured daily for the first 7 days after immersion and then weekly for 5 weeks. On day 42 the test specimens were recharged in 2 per cent sodium fluoride solution and fluoride release was measured initially after 24 hours and then every 48 hours. The recharge regimen was repeated for 3 weeks. Both Limerick glass and Fuji-Ortho L.C. demonstrated the characteristic fluoride release pattern of GIC with a rapid elution of fluoride after the first 24 hours followed by a more gradual release profile over the following 2 weeks. Fuji-Ortho L.C. released the greatest quantity of fluoride but the release profile of Limerick glass was more sustained. Concise released negligible amounts of fluoride. Limerick glass and Fuji-Ortho L.C. showed an increase (P < 0.01) in fluoride release following exposure to 2 per cent sodium fluoride that decreased both with time and subsequent exposures to fluoride supplement.

摘要

牙托周围脱钙的预防主要通过有效的口腔卫生来实现,而这取决于患者自身。对于口腔卫生较差的情况,可能的补偿方式是直接粘结剂释放游离氟离子。众所周知,玻璃离子水门汀(GICs)会释放游离氟离子,通过接触含氟溶液可使其得到补充。本体外研究的目的是比较一种新开发的低熔点单相GIC(利默里克玻璃)与两种临床常用材料(即富士正畸L.C.和简洁)的氟释放和吸收情况。每种材料制作10个测试样本,并在37摄氏度的去离子水中储存。浸泡后的前7天每天测量氟释放浓度,之后5周每周测量一次。在第42天,将测试样本在2%的氟化钠溶液中再充电,最初在24小时后测量氟释放,然后每48小时测量一次。再充电方案重复3周。利默里克玻璃和富士正畸L.C.都呈现出GIC典型地氟释放模式,即最初24小时氟快速洗脱,随后2周内释放逐渐减缓。富士正畸L.C.释放的氟量最多,但利默里克玻璃的释放模式更持久。简洁释放的氟量可忽略不计。利默里克玻璃和富士正畸L.C.在接触2%的氟化钠后氟释放增加(P < 0.01),且随时间和后续氟补充暴露而减少。

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