Plotnikov M B, Maslov M Iu, Aliev O I, Vasil'ev A S, Zueva E P, Krylova S G, Shilova N V
Research Institute of Pharmacology, Russian Academy of Medical Sciences, Siberian Branch, Tomsk.
Vopr Onkol. 2001;47(3):335-7.
Tumor process development in rats inoculated with cellular suspension of transplantable Walker's carcinosarcoma-256 involved enhanced thickening of blood on day 7. Treatment with 20 mg/kg cyclophosphamide, thrice a day, every other day, retarded tumor process and brought hemorheologic indices further down, at the same time. Similar treatment of intact rats with cyclophosphamide caused hemorheologic disorders too.
