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[Disorders of blood rheology in Walker's carcinosarcoma-256 and in cyclophosphamide treatment of rats].

作者信息

Plotnikov M B, Maslov M Iu, Aliev O I, Vasil'ev A S, Zueva E P, Krylova S G, Shilova N V

机构信息

Research Institute of Pharmacology, Russian Academy of Medical Sciences, Siberian Branch, Tomsk.

出版信息

Vopr Onkol. 2001;47(3):335-7.

Abstract

Tumor process development in rats inoculated with cellular suspension of transplantable Walker's carcinosarcoma-256 involved enhanced thickening of blood on day 7. Treatment with 20 mg/kg cyclophosphamide, thrice a day, every other day, retarded tumor process and brought hemorheologic indices further down, at the same time. Similar treatment of intact rats with cyclophosphamide caused hemorheologic disorders too.

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