Kiesleva E V, Bersimbaev R I
Tsitologiia. 1975 Jun;17(6):726-8.
The most frequent localization of H-3-pentagasrine was found in the gastric mucosa of rats, a weak incorporation was observed in the cells of duodenum; liver and skeletal muscles showed no incorporation. In the acid-secreting region of gastric mucosa, the labeled pentagastrine was accumulated selectively in the main and endocrin cells, which allowed to suppose the presence of gastrine receptors in these cells. These data, together with the absence of the label over the oxyntic cells, amy evidence for the participation of endocrine histamine-containing cells in the control of hydrochloric acid secretion in the rat stomach.
发现H-3-五肽胃泌素在大鼠胃黏膜中的定位最为常见，在十二指肠细胞中观察到较弱的摄取；肝脏和骨骼肌未显示摄取情况。在胃黏膜的泌酸区域，标记的五肽胃泌素选择性地积聚在主细胞和内分泌细胞中，这表明这些细胞中存在胃泌素受体。这些数据，连同壁细胞上没有标记，证明含组胺的内分泌细胞参与大鼠胃中盐酸分泌的控制。
