Várkonyi T, Varga L, Náfrádi J, Kozma M, Kása P, Varró V
Acta Hepatogastroenterol (Stuttg). 1976 Nov-Dec;23(6):426-9.
An autoradiographic light-microscopic study was made to attempt to follow the course of metabolism and elimination of glycine labelled pentagastrin in rat. It was found that even 10 seconds after the intravenous injection of 14C-labelled pentagastrin, activity can be observed in the liver and in connection with the parietal cells of the gastric mucosa; the radioactive grains remain in the hepatocytes for a prolonged period, whereas they disappear very quickly from the stomach. Activity can be detected in the renal tubuli 2 minutes or more after labelled pentagastrin administration.
进行了一项放射自显影光学显微镜研究，试图追踪大鼠体内甘氨酸标记的五肽胃泌素的代谢过程和消除途径。结果发现，即使在静脉注射14C标记的五肽胃泌素10秒后，肝脏以及与胃黏膜壁细胞相关的部位就可以观察到活性；放射性颗粒在肝细胞中长时间留存，而在胃中很快消失。在给予标记的五肽胃泌素2分钟或更长时间后，在肾小管中可检测到活性。
