Eisen M, Napp H E, Vock R
Urologe A. 1975 May;14(3):132-6.
In patients with carcinoma of the prostate treated with estrogens platelet aggregation is increased. Patients with increased platelet aggregation have a high incidence of cardio-vascular and thrombo-embolic diseases. Platelet aggregation was measured by the platelet-aggregation test (PAT). Platelet aggregation was inhibited by administration of acetyl-salicylic acid (ASS) 2 times 500 mg daily. An aggregation inhibiting effect was found in all 38 patients. To reduce the cardio-vascular complications of estrogens in treating carcinoma of the prostate acetyl-salicylic acid as an adjunct therapy is recommended. A long-term study has been started.
在用雌激素治疗的前列腺癌患者中，血小板聚集增加。血小板聚集增加的患者发生心血管和血栓栓塞性疾病的几率很高。通过血小板聚集试验（PAT）来测量血小板聚集。每天服用2次、每次500毫克的乙酰水杨酸（ASS）可抑制血小板聚集。在所有38名患者中均发现了聚集抑制作用。为降低雌激素治疗前列腺癌时的心血管并发症，建议将乙酰水杨酸作为辅助治疗。一项长期研究已经启动。
