Yilmaz S, Erçöçen A R, Can Z, Yenidünya S, Edali N, Yormuk E
Department of Plastic and Reconstructive Surgery, Cumhuriyet University Medical Faculty, Sivas, Turkey.
Plast Reconstr Surg. 2001 Sep 15;108(4):1054-60; discussion 1061-2. doi: 10.1097/00006534-200109150-00040.
The viability of cartilage grafts has been well documented; however, controversy still exists about the viability of crushed cartilage. Recently, there has been a tendency to use diced cartilage grafts wrapped with oxidized regenerated cellulose (Surgicel) sheets for improving dorsal contour in rhinoplasty. The viability of diced cartilage grafts and the effect of Surgicel on cartilage grafts are not well known. In this study, we used ear cartilage from 18 New Zealand rabbits. Cartilage grafts were transplanted to surgically created subcutaneous pockets on the back of the rabbits on both the left and right sides. There were three groups: (1) intact cartilage grafts, (2) crushed cartilage grafts, and (3) diced cartilage grafts. The grafts that were transplanted to the right side were wrapped with Surgicel. Cartilage grafts in all groups were viable. In grafts that were wrapped with Surgicel, a marked increase in the collagen content was investigated. Grafts that were wrapped with Surgicel demonstrated no evidence of proliferation, whereas the bare cartilage grafts demonstrated significant amounts of proliferation.
软骨移植物的存活情况已有充分记录;然而,关于粉碎软骨的存活仍存在争议。最近,有一种趋势是使用包裹有氧化再生纤维素(外科用纤维素)片的 diced 软骨移植物来改善鼻整形术中的鼻背轮廓。diced 软骨移植物的存活情况以及外科用纤维素对软骨移植物的影响尚不清楚。在本研究中,我们使用了 18 只新西兰兔的耳软骨。将软骨移植物移植到兔子背部通过手术创建的皮下囊袋中,左右两侧均进行。分为三组:(1)完整软骨移植物,(2)粉碎软骨移植物和(3)diced 软骨移植物。移植到右侧的移植物用外科用纤维素包裹。所有组的软骨移植物均存活。在用外科用纤维素包裹的移植物中,研究发现胶原蛋白含量显著增加。用外科用纤维素包裹的移植物未显示增殖迹象,而裸露的软骨移植物则显示出大量增殖。