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评价绿茶提取物预防下颌后牙拔除后牙龈出血的效果:一项随机对照试验。

Evaluation of the effect of green tea extract on the prevention of gingival bleeding after posterior mandibular teeth extraction: a randomized controlled trial.

机构信息

Department of Clinical Pharmacy and Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.

Department of Oral and Maxillofacial Surgery, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Evid Based Complement Alternat Med. 2014;2014:857651. doi: 10.1155/2014/857651. Epub 2014 Jun 12.

Abstract

Background. Removing tooth results in gingival bleeding. Several measures are taken to stop bleeding. In this study, the effect of green tea extract on cessation of bleeding and oozing after removing of mandibular molars was investigated. Methods. This was a randomized controlled clinical trial carried out on 62 patients who were referred for extraction of their mandibular molars. The volunteers were randomly and equally divided into treatment and control groups. In the first group, green tea extract-impregnated sterile gauze was used after removing the tooth while in the second group, green tea extract-free gauze was applied. Active bleeding and oozing monitoring was done every 5 minutes until cessation of bleeding and one hour after that, respectively. The results were compared using t-test. Results. The mean ± SD of bleeding duration in green tea group was significantly lower than control group (5.87 ± 1.76 versus 10.09 ± 3.61 minutes, P = 0.001). In addition, the number of people with oozing one hour after surgery was significantly lower in the green tea group (6 versus 29 persons, P = 0.001). Conclusion. This study showed that green tea extract contributes to significant decline in bleeding of the socket caused by tooth extraction as well as reduction of oozing.

摘要

背景

拔牙会导致牙龈出血。有几种措施可以止血。本研究旨在探讨绿茶提取物对上颌磨牙拔除后止血和渗血的影响。

方法

这是一项随机对照临床试验,共纳入 62 例因上颌磨牙拔除而就诊的患者。志愿者被随机分为两组,每组 31 例。在第一组中,在拔牙后使用浸有绿茶提取物的无菌纱布,而在第二组中,使用不含绿茶提取物的纱布。分别在 5 分钟和 1 小时后监测活动性出血和渗血情况。使用 t 检验比较结果。

结果

绿茶组的出血持续时间(5.87±1.76 分钟)明显短于对照组(10.09±3.61 分钟),差异有统计学意义(P=0.001)。此外,绿茶组术后 1 小时渗血的人数明显少于对照组(6 例 vs. 29 例),差异有统计学意义(P=0.001)。

结论

本研究表明,绿茶提取物对上颌磨牙拔除后牙槽窝出血和渗血有显著减少作用。

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