Kreiser D, el-Sayed Y Y, Sorem K A, Chitkara U, Holbrook R H, Druzin M L
Department of Gynecology and Obstetrics, Stanford University School of Medicine, Stanford, California, USA.
J Reprod Med. 2001 Aug;46(8):743-6.
To evaluate the perinatal outcomes of pregnancies complicated by isolated decreased amniotic fluid volume (AFI) after 30 weeks' gestation (AFI < or = 5 or > 5 cm but < 2.5th percentile).
We retrospectively studied 150 low-risk singleton pregnancies > 30 weeks' gestation with decreased AFI. We also compared the outcomes of 57 pregnancies with AFI < or = 5 cm to those of 93 pregnancies with AFI > 5 cm but < 2.5th percentile (borderline AFI). Pregnancy outcome was assessed with respect to antepartum, intrapartum and neonatal measures. Statistical significance (P < .05) between groups was determined by means of the Student t test and chi 2 analysis.
There were no statistically significant differences between pregnancies with AFI < or = 5 cm and those with AFI > 5 cm but < 2.5th percentile with respect to labor induction for an abnormal nonstress test (7.0% vs. 7.5%, overall 7.3%), cesarean sections for fetal heart rate abnormalities (7.0% vs. 7.5%, overall 7.3%), presence of meconium (16.1% vs. 15.7%, overall 16%) and Apgar score < 7 at five minutes (0 vs. 1.1%, overall 0.66%). There were no perinatal deaths in either group. Antepartum variable decelerations were more common in pregnancies with AFI < or = 5 cm as compared to those with AFI > 5 cm but < 2.5th percentile (63.1% vs. 45.1%, P = .007; overall 53.3%).
With antepartum monitoring, perinatal outcome in low-risk pregnancies with an isolated decreased AFI after 30 weeks' gestation (< or = 5 or > 5 cm but < 2.5th percentile) appears to be good.
评估妊娠30周后单纯羊水过少(羊水指数[AFI]≤5或>5cm但<第2.5百分位数)的围产期结局。
我们回顾性研究了150例妊娠30周后羊水过少的低风险单胎妊娠。我们还比较了57例AFI≤5cm的妊娠结局与93例AFI>5cm但<第2.5百分位数(临界AFI)的妊娠结局。从产前、产时和新生儿指标方面评估妊娠结局。通过学生t检验和卡方分析确定组间的统计学显著性(P<0.05)。
AFI≤5cm的妊娠与AFI>5cm但<第2.5百分位数的妊娠在以下方面无统计学显著差异:因无应激试验异常而行引产(7.0%对7.5%,总体7.3%)、因胎儿心率异常而行剖宫产(7.0%对7.5%,总体7.3%)、有胎粪(16.1%对15.7%,总体16%)以及5分钟时阿氏评分<7(0对1.1%,总体0.66%)。两组均无围产期死亡。与AFI>5cm但<第2.5百分位数的妊娠相比,AFI≤5cm的妊娠产前变异减速更常见(63.1%对45.1%,P = 0.007;总体53.3%)。
通过产前监测,妊娠30周后单纯羊水过少(≤5或>5cm但<第2.5百分位数)的低风险妊娠围产期结局似乎良好。