Jamal Ashraf, Kazemi Maryam, Marsoosi Vajiheh, Eslamian Laleh
Department of Obstetrics and Gynecology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Int J Reprod Biomed. 2016 Nov;14(11):705-708.
Normal amniotic fluid predicts normal placental function, fetal growth and fetal well-being.
To determine adverse pregnancy outcomes in borderline amniotic fluid index (AFI).
Pregnant women (37-40 wks) with diagnosis of borderline AFI between December 2012 and August 2014 were identified. Antepartum, intrapartum and neonatal data were collected and compared with those of pregnant women with normal AFI. An AFI less than 8 and more than 5 cm was defined for borderline AFI. Pregnancy outcomes included Cesarean section for non-reassuring fetal heart rate, meconium stained amniotic fluid, 5-min Apgar score <7, low birth weight, umbilical cord blood pH at term and NICU admission.
Gestational age at delivery in pregnancies with borderline AFI was significantly lower than normal AFI. Cesarean section rate for non-reassuring fetal heart rate in women of borderline AFI was significantly higher and there was an increased incidence of birth weight less than 10 percentile for gestation age in borderline AFI group. Incidence of low Apgar score and low umbilical artery pH in pregnancies with borderline AFI was significantly higher than women with normal AFI. There were no significant difference in the rate of NICU admission and meconium staining in both groups.
There are significant differences for adverse pregnancy outcomes , such as Cesarean section due to non-reassuring fetal heart rate, birth weight less than 10 percentile for gestation age, low 5 min Apgar score and low umbilical artery pH between pregnancies with borderline and normal AFI.
正常羊水预示着正常的胎盘功能、胎儿生长及胎儿健康状况。
确定羊水指数(AFI)临界值时的不良妊娠结局。
确定2012年12月至2014年8月诊断为AFI临界值的孕妇(37 - 40周)。收集产前、产时及新生儿数据,并与AFI正常的孕妇进行比较。AFI小于8cm且大于5cm定义为AFI临界值。妊娠结局包括因胎儿心率异常行剖宫产、羊水粪染、5分钟阿氏评分<7分、低出生体重、足月时脐血pH值及入住新生儿重症监护病房(NICU)。
AFI临界值的孕妇分娩时的孕周显著低于AFI正常者。AFI临界值的孕妇因胎儿心率异常行剖宫产的比例显著更高,且AFI临界值组出生体重低于孕周第10百分位数的发生率增加。AFI临界值的孕妇低阿氏评分和低脐动脉pH值的发生率显著高于AFI正常的孕妇。两组入住NICU的比例及羊水粪染情况无显著差异。
AFI临界值和正常的孕妇在不良妊娠结局方面存在显著差异,如因胎儿心率异常行剖宫产、出生体重低于孕周第10百分位数、5分钟阿氏评分低及脐动脉pH值低。