Guilleminault C, Eldridge F L, Simmon F B, Dement W C
West J Med. 1975 Jul;123(1):7-16.
Of 250 patients referred to the Stanford Sleep Disorders Clinic, 35 were diagnosed for a sleep induced apnea syndrome. Thirty of them (27 adults and 3 children) were nonobese and complained of a sleep disorder. In 12 patients (9 adults and 3 children) extensive cardiorespiratory workups were done during sleep and wakefulness. Three types of sleep induced apnea syndrome were identified: diaphragmatic (or central), obstructive and mixed. The diaphragmatic type was predominant in sleep apnea insomnia; obstructive was predominant in sleep apnea hypersomnia. Hemodynamic changes were documented during sleep. Tracheostomy, done in two cases, improved the sleep induced symptomatology.
在被转诊至斯坦福睡眠障碍诊所的250名患者中,35人被诊断为睡眠诱发呼吸暂停综合征。其中30人(27名成人和3名儿童)并非肥胖患者,且均有睡眠障碍的主诉。12名患者(9名成人和3名儿童)在睡眠和清醒状态下均接受了全面的心肺功能检查。共识别出三种类型的睡眠诱发呼吸暂停综合征:膈肌型(或中枢型)、阻塞型和混合型。膈肌型在睡眠呼吸暂停失眠症中占主导;阻塞型在睡眠呼吸暂停嗜睡症中占主导。睡眠期间记录到了血流动力学变化。两例患者接受了气管造口术,术后睡眠诱发症状有所改善。