Kraus N, Bradlow A R, Cheatham M A, Cunningham J, King C D, Koch D B, Nicol T G, Mcgee T J, Stein L K, Wright B A
Departments of Communication Sciences, Neurobiology and Physiology, Otolaryngology, Northwestern University, Frances Searle Building, 2299 N. Campus Dr., Evanston, IL 60208, USA.
J Assoc Res Otolaryngol. 2000 Aug;1(1):33-45. doi: 10.1007/s101620010004.
The neural representation of sensory events depends upon neural synchrony. Auditory neuropathy, a disorder of stimulus-timing-related neural synchrony, provides a model for studying the role of synchrony in auditory perception. This article presents electrophysiological and behavioral data from a rare case of auditory neuropathy in a woman with normal hearing thresholds, making it possible to separate audibility from neuropathy. The experimental results, which encompass a wide range of auditory perceptual abilities and neurophysiologic responses to sound, provide new information linking neural synchrony with auditory perception. Findings illustrate that optimal eighth nerve and auditory brainstem synchrony do not appear to be essential for understanding speech in quiet listening situations. However, synchrony is critical for understanding speech in the presence of noise.
感觉事件的神经表征依赖于神经同步。听觉神经病是一种与刺激时间相关的神经同步障碍，为研究同步在听觉感知中的作用提供了一个模型。本文展示了一位听力阈值正常的女性罕见听觉神经病病例的电生理和行为学数据，从而能够将可听性与神经病区分开来。实验结果涵盖了广泛的听觉感知能力和对声音的神经生理反应，提供了将神经同步与听觉感知联系起来的新信息。研究结果表明，在安静聆听情况下，最佳的第八神经和听觉脑干同步对于理解语音似乎并非必不可少。然而，同步对于在有噪声情况下理解语音至关重要。
