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[霍乱弧菌01群和0139群作用的比较病理形态学评估]

[Comparative pathomorphological assessment of the action of Vibrio cholerae serogroups 01 and 0139].

作者信息

Isupov I V, Bugorkova S A

机构信息

Research Institute for Plague Control Microbe, Saratov, Russia.

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 2001 Mar-Apr(2):6-9.

Abstract

The pathomorphological picture of experimental infection caused by the infective agent of cholera was shown to have some specific features observed in infections caused by vibrios belonging to the serogroups under study. Infection caused by V. cholerae of serogroup O139 induced some morphological changes in the gastrointestinal tract which were quite characteristic of this disease, but inflammatory changes with the prevalence of proliferative infiltrative processes came to the foreground simultaneously with less developed processes of edema and dystrophic lesions of enterocytes. These specific morphological features in animals infected with V. cholerae of serogroup O139 appeared to be probably due to the production of new surface structures by these strains.

摘要

霍乱病原体引起的实验性感染的病理形态学表现显示出一些在研究的血清群弧菌引起的感染中观察到的特定特征。O139血清群霍乱弧菌引起的感染在胃肠道诱发了一些该疾病相当典型的形态学变化,但在水肿和肠上皮细胞营养不良性病变发展程度较低的同时,以增殖性浸润过程为主的炎症变化也凸显出来。感染O139血清群霍乱弧菌的动物体内这些特定的形态学特征似乎可能是由于这些菌株产生了新的表面结构。

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