[Effect of neuroendocrine factors on reparation histogenesis of the pancreas during cultivation in the body].

Morphofunctional changes of the pancreas were studied in adult male rats after cultivation by Lazarenko method and in diffusion chambers. The implants were examined on post cultivation d 1,3,6,8,10. The implantation of the pancreatic tissues with hypothalamic neuropeptidergic (supra optic) nuclei was also performed using light and electron microscopy and histochemistry. Hypothalamic neuropeptide (oxytocin and vasopressin) were stated to be interlevel regulatory factors of proliferation, growth and cytodifferentiation of the epithelium and connective tissue cells of the pancreas. Hypothalamic neurohormones influence the maintenance of secretory epithelium viability.