Katilius M, Velanovich V
Division of General Surgery, Henry Ford Hospital, Detroit, Michigan 48202-2689, USA.
JSLS. 2001 Jul-Sep;5(3):227-31.
Achalasia is a relatively rare disorder with a variety of treatment options. Although laparoscopic Heller myotomy has become the surgical treatment of choice, little data exist on the overall quality of life of patients undergoing this technique versus standard open approaches.
We prospectively evaluated all patients surgically treated for achalasia by a single surgeon. Laparoscopic Heller myotomy consisted of a long (> or = 6 cm) esophageal cardiomyotomy extending at least 2 cm onto the gastric cardia, with a concomitant Dor fundoplication. Patients were evaluated preoperatively and postoperatively for symptoms and quality of life using the SF-36, a standardized, generic quality of life instrument.
A total of 23 patients were surgically treated: 15 patients had a planned laparoscopic procedure, with 3 conversions; 8 had planned open procedures. Dysphagia resolved in 20 of 21 patients, with 1 patient in the laparoscopic group requiring reoperation due to an inadequate gastric myotomy. Compared with preoperative scores, a statistically significant improvement occurred in the general health domain of the SF-36 (70 to 82, P = 0.04). Compared with that in patients undergoing open surgery, the laparoscopic group had better scores in the domains of physical functioning and bodily pain.
Laparoscopic Heller myotomy has comparable success to open Heller myotomy, and causes less early detriment to quality of life. This should be the primary treatment in all fit surgical patients with achalasia.
贲门失弛缓症是一种相对罕见的疾病,有多种治疗选择。尽管腹腔镜下Heller肌切开术已成为手术治疗的首选方法,但与标准开放手术相比,关于接受该技术治疗的患者的总体生活质量的数据却很少。
我们对由单一外科医生进行手术治疗的所有贲门失弛缓症患者进行了前瞻性评估。腹腔镜下Heller肌切开术包括一个长(≥6 cm)的食管贲门肌切开术,至少延伸至胃贲门2 cm,并同时进行Dor胃底折叠术。使用标准化的通用生活质量工具SF-36对患者术前和术后的症状及生活质量进行评估。
共有23例患者接受了手术治疗:15例计划进行腹腔镜手术,其中3例中转;8例计划进行开放手术。21例患者中有20例吞咽困难得到缓解,腹腔镜组中有1例患者因胃肌切开术不足而需要再次手术。与术前评分相比,SF-36的总体健康领域有统计学意义的改善(从70提高到82,P = 0.04)。与接受开放手术的患者相比,腹腔镜组在身体功能和身体疼痛领域的得分更高。
腹腔镜下Heller肌切开术与开放Heller肌切开术的成功率相当,且对生活质量的早期损害较小。这应成为所有适合手术的贲门失弛缓症患者的主要治疗方法。