Mehl M L, Withrow S J, Seguin B, Powers B E, Dernell W S, Pardo A D, Rosenthal R C, Dolginow S Z, Park R D
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523, USA.
J Am Vet Med Assoc. 2001 Sep 1;219(5):614-7. doi: 10.2460/javma.2001.219.614.
Spontaneous regression of primary malignant bone tumors is rare but has been reported in the human literature. To the authors' knowledge, spontaneous regression of primary bone tumors in dogs or cats has not been reported. Osteosarcoma (OSA) is the most common primary bone tumor in humans, and it has been reported that the incidence of OSA is 40 to 50 times greater in dogs than humans. In this report, high-grade OSA was diagnosed in biopsy specimens obtained from 4 dogs that subsequently underwent spontaneous regression without tumor-specific treatment. Osteosarcoma in dogs has characteristics similar to that of OSA in humans.
原发性恶性骨肿瘤的自发消退很少见，但在人类文献中有报道。据作者所知，犬猫原发性骨肿瘤的自发消退尚未见报道。骨肉瘤（OSA）是人类最常见的原发性骨肿瘤，据报道，犬骨肉瘤的发病率比人类高40至50倍。在本报告中，从4只犬获取的活检标本中诊断出高级别骨肉瘤，这些犬随后未经肿瘤特异性治疗而出现自发消退。犬骨肉瘤具有与人类骨肉瘤相似的特征。
