人类与犬骨肉瘤的比较生物学
Comparative biology of human and canine osteosarcoma.
作者信息
Mueller F, Fuchs B, Kaser-Hotz B
机构信息
Section of Diagnostic Imaging and Radiation Oncology, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.
出版信息
Anticancer Res. 2007 Jan-Feb;27(1A):155-64.
PMID:17352227
Abstract
Dogs with osteosarcoma provide an important model for the same disease in humans. In this report, the comparative nature of human and canine osteosarcoma including incidence and risk factors, clinical presentation and diagnosis, genetic abnormalities, biologic behaviour and prognostic factors, as well as treatment options are reviewed.
摘要
患有骨肉瘤的犬类为人类的同一种疾病提供了一个重要模型。在本报告中，对人类和犬类骨肉瘤的比较性质进行了综述，包括发病率和风险因素、临床表现和诊断、基因异常、生物学行为和预后因素，以及治疗选择。
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