Dunaev G S, Zykin L F, Bondarev I N
Zh Mikrobiol Epidemiol Immunobiol. 1975 Jun(6):81-5.
In studying the pathogenicity of nonagglutinating vibrios it was established that the majority of the strains isolated from the patients suffering from enteritis possessed enteropathogenic properties which were revealed in the trials on nursling rabbits and on the isolated intestinal loop a of an adult rabbit. In difference to the cholera vibryos, these microorganisms produced no typical cholerogenicity syndrome expressing, however, a number of enteropathogenic properties: caused diarrhea, overfilling of the intestine with fluid, etc. Autopsy showed a typical enterocolitis picture, confirmed by histological studies. Nonagglutinating vibrio cultures isolated from the water and from healthy persons possessed no enteropathogenic properties. An isolated intestinal loop of an adult rabbit proved to be the most sensitive experimental model.
在研究非凝集性弧菌的致病性时发现，从患肠炎的患者中分离出的大多数菌株具有肠道致病特性，这在对乳兔和成年兔离体肠袢的试验中得到了证实。与霍乱弧菌不同，这些微生物不会产生典型的致霍乱综合征，但表现出一些肠道致病特性：引起腹泻、肠内液体充盈等。尸检显示出典型的小肠结肠炎症状，组织学研究也证实了这一点。从水中和健康人身上分离出的非凝集性弧菌培养物不具有肠道致病特性。成年兔的离体肠袢被证明是最敏感的实验模型。
