Viljanto J, Thomasson B, Pikkarainen J, Raekallio J
Acta Chir Scand. 1975;141(2):85-9.
Foetal connective tissue regeneration was studied by implanting 3 x 10 mm cylindrical viscose cellulose sponges subcutaneously in foetal, newborn, and full-grown rabbits. The implants were removed 2 to 7 days later, the foetal implants all being removed after delivery, and were analysed biochemically. In foetal implants a rapid accumulation of soluble forms of collagen took place, while the relative amount of other tissue proteins remained rather low. Connective tissue regeneration of the newborns ressembled, in this respect, that of the full-growns. The results suggest an enhanced production of miniature type collagen in the context of foetal connective tissue regeneration.
通过将3×10毫米的圆柱形粘胶纤维素海绵皮下植入胎儿、新生和成年兔子体内,研究了胎儿结缔组织再生情况。2至7天后取出植入物,胎儿植入物在分娩后全部取出,并进行生化分析。在胎儿植入物中,可溶性胶原蛋白迅速积累,而其他组织蛋白的相对含量仍然较低。在这方面,新生儿的结缔组织再生与成年动物相似。结果表明,在胎儿结缔组织再生过程中,微型胶原蛋白的产生有所增强。