Lambiris A G, Newman P L
Department of Dermatology, Derriford Hospital, Plymouth, UK.
Dermatology. 2001;203(1):63-5. doi: 10.1159/000051707.
Marginal papular acrokeratoderma (MPA) encompasses a group of disorders that share crateriform, keratotic papules along the margins of the hands and feet. We report a unique case of a Philippino woman, with focal acral hyperkeratosis (FAH) associated with sensorineural hearing loss. The clinical phenotype of FAH (hereditary MPA without elastorrhexis) is expanded and the hypothesis of a racially limited disorder is weakened. Effective treatment of this embarrassing condition with acitretin is demonstrated.
边缘丘疹性肢端角化病(MPA)包括一组在手和脚边缘有火山口状角化性丘疹的疾病。我们报告了一例独特的菲律宾女性病例,其患有伴有感音神经性听力损失的局限性肢端角化过度(FAH)。FAH(无弹性纤维离解的遗传性MPA)的临床表型得到扩展,种族局限性疾病的假说也被削弱。展示了用阿维A有效治疗这种令人尴尬病症的方法。